![]() We previously showed that sickle cell patients with high blood viscosity usually have more frequent vaso-occlusive crises than those with low blood viscosity. In this context, any increase in blood viscosity can promote vaso-occlusive like events. However, in sickle cell disease (SCD) vascular function is impaired. This is the case in healthy individuals when vascular function is intact and able to adapt to blood rheological strains. Indeed, any increase in blood viscosity should promote vasodilation. However, blood viscosity, through its effects on wall shear stress, is a key modulator of nitric oxide (NO) production by the endothelial NO-synthase. Poiseuille’s Law predicts that any increase in blood viscosity should cause a rise in vascular resistance. Indeed, any changes in one or several of these parameters may affect blood viscosity differently. Blood flow in the microcirculation is highly dependent on the ability of RBC to deform, but RBC deformability also affects blood flow in the macrocirculation since a loss of deformability causes a rise in blood viscosity. RBC aggregation occurs at low shear rates, and increases blood viscosity and depends on both cellular (RBC aggregability) and plasma factors. The shear thinning property of blood is mainly attributed to red blood cell (RBC) rheological properties. Both hematocrit and plasma viscosity influence blood viscosity. Blood viscosity is an important determinant of local flow characteristics, which exhibits shear thinning behavior: it decreases exponentially with increasing shear rates. ![]()
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When those immigrants came to the United States at the end of the 19th century, and up until just the beginning of the second World War.whatever kind of Yiddish they were using got mixed with English, and there was something that emerged that I've called Yinglish, that is a mixing of Yiddish and English, that is very similar to Spanglish, or could be very similar to Franglais, the mixing of French and English, or the mixing of Portuguese and English, whatever language immigrants use when they come to this country. is the Yiddish that immigrants ended up using when arriving to the new world. There was a Yiddish spoken by Polish Jews, and within Poland, different types of accents, different types of cadences…in the Ukraine another type of Yiddish. īut Yiddish was never a unified, monolithic way of communication. ![]() In 1978, Isaac Bashevis Singer even won the Nobel Prize in Literature for his writing in Yiddish. By the middle of the 20th century and the Holocaust, it had become a full language with its own works of literature. It became a written language in the 16th century. Like Spanglish, Yiddish started as a dialect spoken by people who had migrated away from their homes. The words kvetch, nosh, mishmash, spiel and chutzpah all come from Yiddish, although some have different spellings or connotations. Other languages, like Hebrew and Slavic languages, have influenced it over hundreds of years. It got its start in the 13th century as a German dialect spoken mostly by Jews. Yiddish uses Hebrew characters and its own grammatical structure, but much of its vocabulary has German roots. Ilan StavansĪ good way to understand how Spanglish evolved and continues to grow is to look at a similar linguistic hybrid - Yiddish. Image by Sam Masinter / used courtesy Dr. We'll look at how it compares to a similar hybrid language - Yiddish - in the next section. Spanglish isn't the first hybrid to have gained this kind of prevalence or to have become part of a community identity. ![]() At the same time, it may function as one step in the process of learning English. Spanglish also has some of the earmarks of an internal tongue, a language or dialect that an ethnic group uses to differentiate itself from other groups. Many pidgins start out as lingua francas, or trade languages that speakers of different languages use to communicate with one another. Some linguists refer to it as a pidgin - a language with a simplified grammar and syntax that people without a common language can use. In spite of its prevalence in many Hispanic communities, Spanglish isn't really a language or a dialect. The different styles of Spanglish can also vary in different age groups, with younger speakers using different terms than older speakers. People in San Antonio or in Houston, or Mexicans in New York or Chicago will use different patterns, depending on the contact they have with.the other minorities and the larger mainstream society," Stavans says. In addition, "The Mexican American community doesn't speak one type of Spanglish. They also have their own names, such as Cubonics for the Spanglish spoken by Cuban Americans or Nuyorican for the Spanglish spoken by Puerto Ricans living in New York. Each of these Spanglishes has its own patterns, its own idiosyncrasies. is different form the Spanglish spoken by Cuban Americans in Miami or the Spanglish spoken by Puerto Ricans in New York. The Spanglish spoken by Mexican Americans in, say, L.A. 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Stiegl Brewery in Salzburg, Austria produces arguably one of the most well-known and popular radlers available in the United States market. Instead of simply mixing canned name brand soda, like Sprite or Fanta, with beer, brewers have begun coming up with new ways of making the drink, using all-natural fruit juices and even, in some cases, making their own juices or lemonades to mix with their beer. The innkeeper running the tavern realized he wouldn’t have enough beer to satisfy every cyclist, so he began mixing the beer with citrus soda, thus creating the radler.Įver since, the radler has grown in popularity throughout Germany and Austria but also in the United States market. As the story goes, the beverage got its start in the Bavarian countryside in southeast Germany, when a large group of cyclists arrived at a local tavern, exhausted and parched for beer. The radler, which is the German word for “cyclist,” is a form of beer mixed drink that is typically made by mixing together a light, lager-style beer with citrus juice, lemonade, or soda. As summer fast approaches, the long-awaited days of patio drinking will soon commence, and consumers will be looking for something light, crisp, and refreshing-something they can sip in the sun on a hot summer’s day. ![]() ![]() Hopefully we’ll see theatres back open really soon and we’ll all be able to enjoy live music, live performances once again. ![]() It’s the ultimate, ultimate Les Misérables show tune a superb ensemble number that leaves you with goosebumps because you get to hear so many refrains from the show in this one song.”Īlfie Boe, who has played the role of Jean Valjean in Les Misérables, says: "One Day More is probably one of the biggest highlights of the show and it resonates to everybody who sings it on stage as a unified piece of music and in this present day that we’re living during this pandemic we are unified as a nation, we are unified as a world, we are adapting as a world, we are adapting as human beings, and this song resonates so much with the present situation that we’re in. Get all the lyrics to songs on Songs from Ragtime: The Musical (Studio Cast Recording) and join the Genius community of music scholars to learn the meaning behind the lyrics. Viewed as the 'King of Ragtime,' Scott Joplin was the foremost composer of the genre in the early 20th century, known for works like 'The Maple Leaf Rag' and 'The Entertainer. With its irresistible message of hope (“One day to a new beginning/Raise the flag of freedom high/Every man will be a king”), the song is a worthy winner.Įlaine Paige says: “I wasn’t at all surprised to see ‘One Day More’ take the top spot. Ragtime is an incredibly important American musical-style that was popular during the late 1890s up until 1920, which means youve most likely heard ragtime. The iconic ‘One Day More’ brings together the whole of the cast in a rousing celebration packed with sensational solos. ![]() ![]() ![]() Among its top customers are the United States, India, and Canada. The company has achieved this by selling its products worldwide. ![]() While the product was not featured on the show, the company has risen to a billion dollars in market value. Increasing Net WorthĬurrently, the First Defense Nasal Screens net worth has grown rapidly as a result of the Shark Tank show. In fact, the company sells them to more than 50 countries worldwide. The company is the leading producer of air pollution filters. The company has a global distribution of their products, and their net worth is estimated to reach $1 billion by 2022. Global DistributionĪs of January 2022, the net worth is expected to rise to $100 million in July. However, the company is not open to the public yet. ![]() The FDNS net worth is estimated to reach $1 billion in 2020. Although this business has a small team, it is widely available in more than 50 countries. The company’s revenues are not publicly disclosed, but its net worth comes from the sales of its nose filter products to different markets around the world. A successful venture should never be financed solely on its own. Hence, Joe’s FDNS net worth is quite high. The company is now available in over 50 countries around the world. Although the business is not public, it has become a successful venture in the marketing of the product. In addition to its global success, the First Defense Nasal Screens net worth of Joe Moore is estimated to be $50 million by February 2022. It’s no wonder that the company’s sales have exceeded $100 million in five years. But the idea paid off and First Defense Nasal Screens are now sold in more than 50 countries around the world. In the early years of the company’s existence, Joe had to raise a substantial amount of capital to start up. ![]() World Wideĭespite the burgeoning popularity of FDNS, the company’s finances are confidential. Because of the global demand for these nasal screens, the net worth of the company has increased significantly in the last few years. In addition, the sales of FDNS devices in India are forecasted to reach $50 million by August 2022. His business plans have a strong chance of becoming a global company. In 2017, the company won the $1 million prize for best idea. Joe Ross was a successful Shark on Shark Tank. The business will likely continue to grow with no outside investment, thanks to its ability to reduce air pollution and protect human health. Despite the low valuation, the FDNS company is profitable, and Joe Moore has a net worth of around $5 million. The company’s net worth is estimated at $50 million by February 2022. The founders are now based in Shanghai, China, and Australia. Originįirst Defense Nasal Screens started in the United States, but is now distributed worldwide. By the end of the year, the net worth of the business is expected to grow to $50 million. The business later received an $8 million purchase order signed by Hillary Clinton for the United Arab Emirates, which was facing severe air pollution. Despite declining the offer, the investors saw potential and offered him $750,000 for a 30% stake in the company and 10% lifetime royalty. He turned down $4 million from Shark Tank investors for a 30% stake in the company and a 10% perpetual royalty. The First Defense Nasal Screens company is owned by Joe Moore. ![]() |
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